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產(chǎn)品詳情
  • 產(chǎn)品名稱:爪腫測量儀

  • 產(chǎn)品型號:37140
  • 產(chǎn)品廠商:意大利UGO
  • 產(chǎn)品價(jià)格:0
  • 折扣價(jià)格:0
  • 產(chǎn)品文檔:
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簡單介紹:
爪腫測量儀計(jì)用于測量抗腫藥的效果.爪腫測量儀使用方法簡單,將腫脹的大鼠爪放入儀器的水槽中,導(dǎo)致水平面上升,爪腫測量儀測量出水平面上升引起的水壓力變化值,該壓力變化值對應(yīng)伸入水中腫脹大鼠爪的體積;
詳情介紹:

產(chǎn)品品牌:意大利UGO

產(chǎn)品型號:37140



爪腫測量儀設(shè)計(jì)用于風(fēng)濕關(guān)節(jié)炎、水腫、藥理作用等研究,精準(zhǔn)測量嚙齒類動(dòng)物肢體的腫脹情況。自上世紀(jì)60年代起,已經(jīng)有超過1000篇的引文。該儀器是大、小鼠炎癥水腫測量的理想工具,其測量分辨率是0.01ml。
 

整套儀器包含一個(gè)腳踏開關(guān),用于記錄讀數(shù),從而使得操作人員可以全神貫注于將動(dòng)物的爪侵沒于測量水杯中。液晶屏實(shí)時(shí)顯示實(shí)驗(yàn)數(shù)據(jù),通過相應(yīng)軟件可方便的將實(shí)驗(yàn)數(shù)據(jù)導(dǎo)入電腦。





爪腫測量儀使用方法簡單,將腫脹的大鼠爪放入儀器的水槽中,導(dǎo)致水平面上升,爪腫測量儀測量出水平面上升引起的水壓力變化值,該壓力變化值對應(yīng)伸入水中腫脹大鼠爪的體積;對大鼠服用抗腫脹藥,大鼠的爪相應(yīng)消腫,將消腫的大鼠爪放入水槽中,導(dǎo)致水平面上升,爪腫測量儀測量出水平面上升引起的水壓力變化值,該壓力變化值對應(yīng)伸入水中消腫大鼠爪的體積,根據(jù)兩次水壓力變化值即體積的差值評估得出抗腫脹藥的效果。


特征

  • 腳踏記錄實(shí)驗(yàn)數(shù)據(jù)
  • 超過1000引文
  • 多測量水杯可選


優(yōu)點(diǎn)

  • 免手持操作
  •  絕大多數(shù)應(yīng)用開在參考文獻(xiàn)中查到
  •  可用于大、小鼠實(shí)驗(yàn)


規(guī)格參數(shù):

  • 測量水杯直徑:1.3 cm (小鼠), 1.8; 2.5 & 3.5 cm (大鼠)
  • 讀數(shù)分別率:0.01ml
  • 與電腦連接:串行接口或USB接口
  • 軟件:包含在標(biāo)配中

參考文獻(xiàn):

  et alia: “A2A Adenosine Receptors Are Differentially Modulated by Pharmacological Treatments in Rheumatoid Arthritis Patients and Their Stimulation Ameliorates Adjuvant-Induced Arthritis in Rats” PLoS ONE 8(1): e54195, 2013


§ T. Bertaim et alia: “Dose and Administration Schedule Effect of Tiludronate on Joint Damage in the Model of Complete Freund Adjuvant Induced Monoarthritis in Rats” Open Journal of Rheumatology and Autoimmune Diseases 3: 18-25, 2013


§ E. Borbély et alia: “Role of Tachykinin 1 and 4 Gene-Derived Neuropeptides and the Neurokinin 1Receptor in Adjuvant-Induced Chronic Arthritis of the Mouse” PLoS ONE 8(4): e61684,2013

§ R. Korhonen et alia: “Attenuation of TNF production and experimentally induced inflammation by PDE4 inhibitor rolipram is mediated by MAPK phosphatase-1” Br. J. Pharmacol. 169 (7):1525-1536, 2013


§ A. Finlay et alia: “Sphingosine 1-Phosphate Mediates Hyperalgesia via a Neutrophil-Dependent Mechanism” PLoS ONE 8(1): e55255, 2013


§ D. Piomelli et alia:” Anandamide suppresses pain initiation through a peripheral endocannabinoid mechanism”. Nature NSC, 2010

§ L.H. Santos et alia: "Anti-Inflammatory, antinociceptive and Ulcerogenic Activity of a Zinc-Diclofenac Complex in Rats" Brazil. J. Med. Biol. Res. 37: 1205-1213, 2004

§ D.W. Li et alia: "Antiinflammatory Activity of a α-Hederin methyl Ester from the Alkaline Hydrolysate of the Butanol Fraction of Kalopanax Pictus Bark Extract" Biol. Pharm. Bull. 26 (4): 429-433, 2003
 
§ A. Rotelli et alia: “Comparative Study of Flavonoids in Experimental Models of Inflammation” Pharmacol. Research 48: 601-606, 2003
 
§ H. Machelska et alia: "Opioid Control of Inflammatory Pain Regulated by Intercellular Adhesion Molecule-1" J. Neuroscience 22 (13), 5588-5596, 2002
 
§ W. Binder & J. Walker: "Effect of the Peripherally Selective Κ-Opioid Agonist, Asimadoline, on Adjuvant Arthritis" Br. J. Pharmacol. 124: 647-654, 1998
§ F. Vincenzi


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